Senior Research Associate, DMPK

Location: San Francisco, CA


  • Performs routine in vitro DMPK experiments including but not limited to hepatocyte stability, microsomal stability and plasma stability assays according to defined protocols under general guidance
  • Method development of quantitative/semi-quantitative analysis for in vitro ADME study samples
  • Operates LC/MS/MS system to produce quantitative/semi-quantitative data for in vitro ADME studies and maintains LC/MS/MS system on a routine basis
  • Programs, operates and maintains fully automated liquid handler system for in vitro ADM experiments (Workstation-Zephyr)
  • Maintains accurate and well-organized laboratory records and notebooks
  • Makes detailed observations and will analyze, interpret, compile, summarize, data and present conclusions
  • Prepares technical reports, summaries, and/or protocols when necessary
  • Develops methods and procedures on new assignments when necessary
  • Assists with the investigation, creation and development of methods, experiments and/or technologies for project advancement
  • Maintains familiarity with current scientific literature
  • Maintains compliance to company Environmental Health and Safety policies, procedures and practices


  • Minimum of a Bachelor’s degree in a scientific discipline is required, equivalent experience may be accepted
  • Minimum of 8 years work experience in a research and/or development environment is required
  • Must have excellent analytical skills, with significant hands on laboratory experience
  • Must have a demonstrated working knowledge of scientific principles
  • Must be able to demonstrate good decision –making skills
  • Must possess excellent oral and written communication skills
  • Must be able to independently write reports
  • Must be able to demonstrate sound judgment within broadly defined practices and policies
  • Must have demonstrated problem solving abilities
  • Strong organizational skills are required
  • Good computer skills are required
  • Working knowledge of MS Word, Excel, PowerPoint is required
  • Experience working in a FDA regulated environment is highly desired
  • Must be able to work well in and promote a team environment and demonstrate leadership abilities
  • Must be able to provide technical assistance to others in a wide range of laboratory based activities/techniques